Big news! I am beyond thrilled to announce that I’ll be starting my own lab as a Tenure-Track Assistant Professor at the University of Tennessee Health Science Center (UTHSC) in Jan 2027!

About UTHSC: The Goode Lab will be housed in the Department of Anatomy and Neurobiology within the College of Medicine and the Neuroscience Institute at UTHSC. Located in the heart of Memphis’ Medical District, UTHSC is a public R1 research and medical university and part of Tennessee’s flagship university system. UTHSC is rapidly growing and making major investments in neuroscience (with additional faculty hires on the horizon)—the Goode Lab is excited to be a part of this momentum! UTHSC maintains state-of-the-art research cores in next-gen sequencing/bioinformatics, proteomics/mass spec, small-molecule detection/development, and more. UTHSC is further enriched by strong partnerships with its world-class neighbors, including St. Jude Children’s Research Hospital, Rhodes College, and the University of Memphis. Prospective graduate students can join the Goode Lab though the Neuroscience Track of the Biomedical Sciences Ph.D. Program. Trainees entering the Goode Lab can expect the highest quality of mentorship, scientific rigor, and collaboration across the department and UTHSC!

About Memphis: Recognized as the “Home of the Blues” and the “Birthplace of Rock n’ Roll,” Memphis offers a great balance of city amenities, small-town comforts, and genuine affordability. The city is celebrated for its incredible food, recreation, arts, history, and music scenes—you can eat award-winning Memphis BBQ, enjoy live music on iconic Beale Street, catch games at FedExForum or Autozone Park, hang out in the wonderfully bizarre Bass Pro Shops at the Pyramid, or visit the highly rated Memphis Zoo. Memphis sits directly along the Mississippi River and is home to the massive Shelby Farms Park and Overton Park, offering abundant green space, trails, and outdoor recreation. The city also enjoys easy access to fun neighboring destinations, including Nashville, the Ozarks, and Little Rock. Perhaps most importantly for prospective trainees: serious science is sustainable in Memphis. With a low cost of living and no state income tax, your graduate or postdoctoral stipend goes meaningfully further in Memphis than in most other major research cities. Many trainees and faculty live in vibrant and nearby neighborhoods like Harbor Town, Midtown/Cooper-Young, and East Memphis, as well as neighboring towns like Bartlett, Collierville, and Germantown.

RESEARCH OVERVIEW

Nearly half of all people will experience a mental illness at some point in their lives (NIMH). Newer, improved, and more accessible therapies depend on greater insights into the neurobiological bases of learning, memory, and emotion.

Through its ability to transform experiences into distinct, reactivatable patterns of neural activity, the hippocampus (HPC) supports episodic memory, spatial navigation, and emotional regulation (Goode & Tanaka et al. 2020). HPC dysfunction is implicated in a range of psychiatric and neurological disorders (Maren et al. 2013)—making it a critical target for understanding what goes wrong in mental illness.

How are HPC signals routed to subcortical structures for calibration of adaptive and motivated behaviors? The lateral septum (LS) is uniquely positioned to answer this: it receives convergent input from across the entire HPC (Rizzi-Wise & Wang 2021) and, in turn, broadcasts neuropeptidergic and inhibitory signals to the hypothalamus and broader subcortex. This makes HPC-LS-subcortical interactions a compelling—and underexplored—substrate for motivated behaviors (Besnard & Leroy 2022).

Accordingly, my research program focuses on decoding the genetic, neuroanatomical, and functional organization of these circuits using modern molecular and circuit-level tools (Goode et al. 2026) in preclinical models of feeding, fear, and social behaviors. The goal: to uncover how HPC-LS interactions shape memory and motivation, how they go awry in disease, and how we might rescue their functions!

Stay tuned for additional updates, including about specific research projects, lab developments, and hiring!

Published Works (Click for Links):

(21) Ain Chung**, Jason Bondoc Alipio**, Megha Ghosh***, Liam Evans***, Samara M. Miller, Travis D. Goode, Iyanah Mehta, Omar J. Ahmed, Amar Sahay (2026) Neotenic expansion of adult-born dentate granule cells reconfigures GABAergic inhibition to enhance social memory consolidation. Nature Neuroscience (In Press - Link to Preprint) Equal Contribution**; Equal Contribution***

(20) Cinzia Vicidomini, Travis D. Goode**, Ruilin Yu**, Iyanah Mehta**, Kathleen M. McAvoy, Conor H. Beveridge, Caitlin E. Randolph, Sanjay N. Iyer, Matheus B. Victor, Noelle Leary, Liam Evans, Michael J.B. Steinbaugh, Zon Weng Lai, Marina C. Lyon, Manuel Rico F.S. Silvestre, Giorgia Tosoni, Dilara Ayyildiz, Shannan Ho Sui, Kei Yamamoto, Makoto Murakami, Evgenia Salta, Li-Huei Tsai, Gaurav Chopra, Amar Sahay (2026) An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience. Nature Neuroscience (In Press - Link to Preprint) Equal Contribution**

(19) Yu-Tzu Shih**, Jason Bondoc Alipio**, Zin-Juan Klaft, Alok Nath, Nathaniel Green, Alok Nath Mohapatra, Travis D. Goode, muthu Panchanatham, Devesh Pathak, Lai Ping Wong, Ruslan Sadreyev, Jung Ho Hyun, Omar Ahmed, Chris Dulla, Amar Sahay (2026) Procognitive restoration of PV neuron plasticity in neurodevelopmental disorders. Nature 1-11. PMCID: (in progress); Equal Contribution**

(18) Travis D. Goode, Mollie X. Bernstein**, Michael S. Totty**, Jason Bondoc Alipio**, Cinzia Vicidomini, Devesh Pathak, Antoine Besnard, Delara Chizari, Nina Sachdev, Michael D. Kritzer, Ain Chung, Xin Duan, Evan Macosko, Stephanie C. Hicks, Larry S. Zweifel, Amar Sahay (2026) A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding. Neuron 114: 1–23. PMCID: PMC13288035; Equal Contribution**

(17) Reed L. Ressler**, Travis D. Goode**, Sohmee Kim, Karthik R. Ramanathan, Stephen Maren (2021) Covert capture and attenuation of a hippocampus-dependent memory. Nature Neuroscience 24: 677–684. PMCID: PMC8102347; Equal Contribution**

(16) Travis D. Goode**, Kazumasa Z. Tanaka**, Amar Sahay, Thomas J. McHugh (2020) An integrated index: place cells, engrams and hippocampal memory. Neuron 107: 805–820. PMCID: PMC7486247; Equal Contribution**

(15) Reed L. Ressler, Travis D. Goode, Carolyn Evemy, Stephen Maren (2020) NMDA receptors in the CeA and BNST differentially regulate fear conditioning to predictable and unpredictable threats. Neurobiology of Learning and Memory 174: 107281. PMCID: PMC7484222

(14) Travis D. Goode, Gillian M. Acca, Stephen Maren (2020) Threat imminence dictates the role of the bed nucleus of the stria terminalis in contextual fear. Neurobiology of Learning and Memory 167: 107116. PMCID: PMC6980749

(13) Travis D. Goode, Reed L. Ressler, Gillian M. Acca, Olivia Miles, Stephen Maren (2019) Bed nucleus of the stria terminalis regulates fear to unpredictable threat signals. eLife 8: e46525. PMCID: PMC6456295

(12) Kelly Luyck, Travis D. Goode, Haemy Lee Masson, Laura Luyten (2019) Distinct activity patterns of the human bed nucleus of the stria terminalis and amygdala during fear learning. Neuropsychology Review 29: 181–185. PMCID: PMC6366553

(11) Travis D. Goode, Stephen Maren (2018) Common neurocircuitry mediating drug and fear relapse in preclinical models. Psychopharmacology 236: 415–437. PMCID: PMC6373193

(10) Roger Marek**, Jingji Jin**, Travis D. Goode**, Thomas F. Giustino, Qian Wang, Gillian M. Acca, Roopashri Holehonnur, Jonathan E. Ploski, Paul J. Fitzgerald, Timothy P. Lynagh, Joseph W. Lynch, Stephen Maren, Pankaj Sah (2018) Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear. Nature Neuroscience 21: 384–392. PMCID: PMC5957529; Equal Contribution**

(9) Travis D. Goode, Stephen Maren (2017) Role of the bed nucleus of the stria terminalis in aversive learning and memory. Learning & Memory 24: 480–491. PMCID: PMC5580527

(8) Thomas F. Giustino, Jocelyn R. Seemann, Gillian M. Acca, Travis D. Goode, Paul J. Fitzgerald, Stephen Maren (2017) β-adrenoceptor blockade in the basolateral amygdala, but not the medial prefrontal cortex, rescues the immediate extinction deficit. Neuropsychopharmacology 42: 2537–2544. PMCID: PMC5686500

(7) Travis D. Goode, Crystal M. Holloway-Erickson, Stephen Maren (2017) Extinction after fear memory reactivation fails to eliminate renewal in rats. Neurobiology of Learning and Memory 142: 41–47. PMCID: PMC5457330

(6) Travis D. Goode, Jingji Jin, Stephen Maren (2018) Neural circuits for fear relapse. Pp 182–202, In Neurobiology of Abnormal Emotion & Motivated Behaviors (S Sangha, D Foti, Eds) San Diego: Elsevier. PMCID: N/A

(5) Brooke N. Dulka, Ellen C. Ford, Melissa A. Lee, Nathaniel J. Donnell, Travis D. Goode, Rebecca Prosser, Matthew A. Cooper (2016) Proteolytic cleavage of proBDNF into mature BDNF in the basolateral amygdala is necessary for defeat-induced social avoidance. Learning & Memory 23: 156–160. PMCID: PMC4793198

(4) Travis D. Goode**, Kah-Chung Leong**, Jarid Goodman, Stephen Maren, Mark Packard (2016) Enhancement of striatum-dependent memory by conditioned fear is mediated by beta-adrenergic receptors in the basolateral amygdala. Neurobiology of Stress 3: 74–82. PMCID: PMC5146203; Equal Contribution**

(3) Travis D. Goode, Janice J. Kim, Stephen Maren (2015) Reversible inactivation of the bed nucleus of the stria terminalis blocks reinstatement but not renewal of extinguished fear. eNeuro 2: ENEURO.0037-15.2015. PMCID: PMC4586936

(2) Travis D. Goode, Janice J. Kim, Stephen Maren (2015) Relapse of extinguished fear after exposure to a dangerous context is mitigated by testing in a safe context. Learning & Memory 22: 170–178. PMCID: PMC4340132

(1) Travis D. Goode, Stephen Maren (2014) Animal models of fear relapse. Institute for Laboratory Animal Research (ILAR) Journal 55: 246–258. PMCID: PMC4197897

(Disclaimer: I Do Not Speak For Any Employer Or Funding Agency; All Opinions My Own)